WHO WE ARE
Our Scientists
ELS FIEREMANS
Associate Professor
I am a faculty at the Department of Radiology, Center for Biomedical Imaging, New York University School of Medicine, where I spearhead the MRI Biophysics group, together with Dr. Dmitry Novikov. I graduated Magna Cum Laude in Engineering in Physics from Ghent University in 2003, where I subsequently received my PhD in 2008 on Validation Methods for Diffusion Weighted Magnetic Resonance Imaging in Brain White Matter. I was a postdoctoral fellow at the Center for Biomedical Imaging, New York University School of Medicine during 2008-2011. Currently, my research focuses on early biomarkers for neurodegenerative diseases, novel contrasts from time-dependent diffusion MRI, and numerical simulations and design of MRI phantoms.
RESEARCH INTERESTS
- Monte Carlo simulations and physical phantoms
- Biophysical modeling and subsequent animal validation
- Design of imaging markers for white matter tract integrity describing axonal loss, demyelination and axonal injury from clinically usable diffusion protocols (e.g., diffusional kurtosis imaging) to assess neurodegenerative diseases including Alzheimer’s, multiple sclerosis, traumatic brain injury, cancer, as well as normal development
- Multimodal imaging studies in Alzheimer’s pathology using MR-PET
- Design of imaging markers from time-dependent diffusion in brain, muscular pathologies and prostate cancer
SELECTED PUBLICATIONS
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Chung S, Fieremans E, Novikov DS and Lui YW. Microstructurally informed subject-specific parcellation of the corpus callosum using axonal water fraction. (2024) Brain Struct Funct. 230, 1 Pubmed Brain Struct Funct
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Pan Y, Hong LE, Acheson A, Thompson PM, Jahanshad N, Zhu AH, Yu J, Chen C, Ma T, Liu HL, Veraart J, Fieremans E, Karcher NR, Kochunov P and Chen S. A Site-Wise Reliability Analysis of the ABCD Diffusion Fractional Anisotropy and Cortical Thickness: Impact of Scanner Platforms. (2024) Hum Brain Mapp. 45, e70070 Pubmed Hum Brain Mapp PMC Article
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Lee HH, Novikov DS, Fieremans E and Huang SY. Revealing membrane integrity and cell size from diffusion kurtosis time dependence. (2024) Magn Reson Med. Pubmed Magn Reson Med
AWARDS AND HONORS
- 2020: Hirschl-Weill-Caulier Career Scientist Award for Academic Excellence
- 2014-2015: Fellow, Raymond and Beverly Sackler Laboratories for Convergence of Physical, Engineering and Biomedical Sciences in Honor of Saul J. Farber
- 2013: Junior Investigator of the Charleston Conference on Alzheimer’s Disease
- 2009: Henri Benedictus fellowship, Belgian American Foundation and King Baudouin Foundation